Netanyahu has warned that his country would "have to act" if necessary to keep Syria's vast stockpile of chemical weapons from falling into the hands of militants should the regime in Damascus crumble.
With the bloodshed in Syria intensifying, President Basher Assad's hold is looking tenuous.
Asked if Israel and the US had discussed managing a Syrian collapse, the Israeli government official said on Monday, "You can presume that these sorts of issues came up with American officials when they visited recently in Israel."