Brady, who had a career-equaling best six touchdown passes for the game, connected twice with Randy Moss and Wes Welker and once with Kevin Faulk in the second quarter while building a 45-0 halftime lead. Moss caught a third TD pass in the third quarter from Brady, who passed for 380 yards. New England (4-2) also set team records for points in a game and total offense (619). Tennessee dropped to 0-6. Last season, they posted the NFL's best regular season record of 13-3.
Other NFL results: Green Bay 26, Detroit 0; New Orleans 48, NY Giants 27; Pittsburgh 27, Cleveland 14; Houston 28, Cincinnati 17; Kansas City 14, Washington 6; Carolina 28, Tampa Bay 21; Jacksonville 23, St. Louis 20, OT; Minnesota 33, Baltimore 31; Arizona 27, Seattle 3; Oakland 13, Philadelphia 9; Buffalo 16, NY Jets 13, OT; Atlanta 21, Chicago 14.